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Dear All, I would like to announce the first release of... xia2: Automated Data Reduction xia2 is a new automated data reduction system designed to work from raw diffraction data and a little metadata, and produce usefully reduced data in a form suitable for immediately starting phasing and structure solution, e.g. through Mr BUMP or your favourite experimental phasing suite. The only software which is actually required is CCP4 6.0.1/2 (other data reduction suites will be supported in time) and Python 2.4.x, and the following platforms are supported: - GNU/Linux on i386 (and 64 bit extensions) - OS X 10.4 intel (PPC support will be added if there is demand) - Microsoft Windows 2000/XP (Vista is untested) For more information and downloads please visit the CCP4 prerelease pages or go directly to: http://www.ccp4.ac.uk/xia Regards, Graeme Winter ----------------------------- Development of xia2 is supported by the BBSRC e-HTPX grant and the EU framework 6 BioXHit initiative. xia2 makes extensive use of Phil Evans's program Pointless, and I would like to thank him for the extensive modifications made to the program, and can will also use Labelit if available. I would also like to thank the US structural genomics JCSG group for providing their extensive collection of raw diffraction data to methods developers. Finally I would like to acknowledge CCP4, for without their software this project would go nowhere!