Department: Structural Biology
Location: Berkeley, California 
URL: www.plexxikon.com
Start Date: ASAP
Duration: Perminant
Description: Located in Berkeley, California, Plexxikon is a leader in
the discovery and development of novel small molecule pharmaceuticals to
treat human disease. Since operations commenced June 2001, Plexxikon has
applied its proprietary platform technology to identify and build a
portfolio of product opportunities for therapeutic indications in
metabolic disorders, cardiovascular disease, inflammation and oncology.
We are seeking a highly motivated and experienced X-ray protein
crystallographer in our Structural Biology Department at the level of
Scientist or Senior Scientist depending on qualifications. The
successful candidate will participate in our scaffold-based drug
discovery effort on many exciting therapeutic targets by carrying out
high throughput co-crystal structure determination, co-crystallization
and synchrotron data collection. The incumbent will also participate in
specific drug target project teams and collaborate closely with
scientists from Molecular Biology, Protein Chemistry, Assay Development,
Informatics and Chemistry in shaping the direction of our drug discovery
effort. This position requires a PhD and, for Sr. Scientist, a minimum
of five years of industry experience in drug discovery. Postdoctoral
research experience in related areas will be considered, however
preference will be given to candidates with relevant industrial
experience. Qualified candidates must possess excellent communication
skills and the ability to work in a highly collaborative and team
oriented environment. The ideal candidate will have a track record of
accomplishments demonstrating technical proficiency, independent
thinking, and scientific creativity. Extensive experience with high
throughput co-crystal structure determination and high throughput
co-crystallization are required. Experience with script writing and
programming that facilitates automatic crystallographic structure
determination and related tasks would be a plus. If you are interested
in applying for this opportunity, please submit your resume or CV, a
cover letter and salary requirements to the address below. All
submissions will be evaluated and interviews will be conducted for those
applicants who most strongly fit our needs. If you are not contacted for
an interview, your resume will remain on file and active for available
positions for a period of one year. 
Other details: Plexxikon is an equal opportunity employer.
Please submit: CV, 3 references
Person to contact: Human Resources
Surface mail address: Plexxikon Inc., 91 Bolivar Dr., Berkeley, CA
94710, USA.
Email address: [EMAIL PROTECTED]
Phone number: (510)647-4000
Fax number: (510)647-4090
Job Posted: 05/21/07
Job ID Number: 1179788911

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