*BIOPHYSICIST*
Job # 20882

The Physical Biosciences Division of LBNL is accepting applications for a biophysicist be a part of an interdisciplinary team to help operate, maintain, and improve the small angle X-ray scattering (SAXS) station in the SIBYLS (12.3.1) beamline at the Advanced Light Source (ALS). The successful candidate will conduct collaborative and independent research to address questions of structural cell biology relevant to multi-component protein complexes and conformations. Research focus will be on IDAT (Integrated Diffraction Analysis Technologies) efforts to combine SAXS and crystallography. Specific research programs include the SBDR (Structural Biology of DNA repair) as well as MAGGIE (Molecular Assemblies, Genes, and Genomics Integrated Efficiently).

Approaches may include:
(1) Static and time-resolved studies by SAXS of biological macromolecules in solution
(2) Crystallographic studies of purified protein and those complexes
(3) Integration of crystallographic and solution data to obtain biologically relevant structures (4) Supervised biochemical and biophysical assays to defined functional state and activities of these macromolecular assemblies

*Qualifications:*
*Biophysicist with high level expertise in small angle X-ray scattering
*Research experience in protein crystallography, protein biochemistry, molecular biology and structural biology, especially in relation to DNA repair genes, proteins, and multi-protein complexes *3+ years experience in synchrotron-based research using complex instrumentation and computer controls *Experience with alternative small angel scattering techniques, particularly with home source X-ray scattering and Neutron scattering techniques *Expertise in protein diffraction techniques, biophysical software for structure determinations, or synchrotron instrumentation
*Expertise in molecular dynamics computation

*Note*: This is a one-year, career-track term appointment, renewable based on funding availability and employee performance.
**

Lawrence Berkeley National Laboratory is a world leader in science and engineering research, with 11 Nobel Prize recipients over the past 75 years, and 59 present members of the National Academy of Sciences. LBNL conducts unclassified research across a wide range of scientific disciplines and hosts four national user facilities. AA/EEO employer committed to the development of a safe and diverse workforce. Learn more at www.lbl.gov <http://www.lbl.gov>. **

*To inquire about this position, please contact Dr. John Tainer at [EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>.*

*Please apply* at http://jobs.lbl.gov/LBNLCareers/details.asp?jid=20882&p=1 <http://jobs.lbl.gov/LBNLCareers/details.asp?jid=20882&p=1> in order to be considered for this opportunity. Submit a single attachment including your résumé or CV and letter of interest.

Reference "Internet" and "CCP4BB" as your source.

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Amy Pagsolingan, PHR
Senior Recruiter
Lawrence Berkeley National Laboratory
http://jobs.lbl.gov <http://jobs.lbl.gov/>
510-486-5277 (phone)





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