Dear Yingjie,
This does not answer your question directly but we had a similar problem with our DynaPro purchased from Protein Solutions. Most likely this is due to an optics misalignment or a dead laser. Protein Solutions' products are now available in the US through Wyatt Technology (www.wyatt.com <http://www.wyatt.com/> ). They do undertake repairs of equipment sold by Protein Solutions. In our case, however, we thought the repair was too expensive. We ended up trading in our DynaPro and buying a DynaPro Plate Reader. We found the plate reader to be a much more user-friendly instrument since it eliminates the need to clean the cuvette between reads and can be automated to read from 1-1536 samples (with volumes as low as 5 ul depending on the plate used). Best regards, Priyamvada Priyamvada Acharya, Ph.D. Visiting Fellow Structural Biology Section Vaccine Research Center, NIAID/NIH Building 40, Room 4609B 40 Convent Drive, MSC3027 Bethesda, MD 20892 (301) 594-8711 (Tel) (301) 480-2658 (Fax) ________________________________ From: Yingjie Peng [mailto:[EMAIL PROTECTED] Sent: Saturday, March 29, 2008 11:30 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Problem with the DLS instrument Dear colleagues, We have encountered a problem with our dynamic light scattering instrument DynaPro from Protein Solutions (New Jersey) and would like to solicit your suggestions and advices. The instrument was purchased about six years ago. In the past years, the intensity (Cnt/s) has decreased dramatically to about 200 Cnt/s which practically makes the instrument unusable. We want to repair the instrument but could not find any representative of the company in China. I am wondering if someone could provide us advices on what we should do to get our instrument back to work. Many thanks in advance. Yingjie Yingjie PENG, Ph.D. student Structural Biology Group Shanghai Institute of Biochemistry and Cell Biology (SIBCB) Shanghai Institute of Biological Sciences (SIBS) Chinese Academy of Sciences (CAS) 320 Yue Yang Road, Shanghai 200031 P. R. China 86-21-54921117 Email: [EMAIL PROTECTED]