Post Doctoral Training Fellow Section of Structural Biology, The Institute of Cancer Research
The Institute of Cancer Research (a College of the University of London) is a world-class cancer research organization with HEFCE RAE ratings of international excellence across all of its research programmes. In partnership with The Royal Marsden NHS Foundation Trust, we form the largest comprehensive cancer centre in Europe, dedicated to research that extends from epidemiology, genetics and molecular biology, through drug discovery and development, to cancer diagnosis and patient treatment. This makes us uniquely placed to work towards our vision that people may live their lives free from the fear of cancer as a life threatening disease.
This Cancer Research UK Development Committee funded position will provide structural biology support for the hit-to-lead development of small molecule inhibitors of a protein kinase. The successful applicant will determine crystal structures of the kinase bound to small molecule inhibitors and contribute to the structure-based design of more potent, more specific inhibitors. The project will be carried out in the laboratory of Dr Richard Bayliss (Structural Biology), in collaboration with chemists at the Institute (Centre for Cancer Therapeutics), and the University of Newcastle.
Applicants must hold a PhD, or be close to completing their PhD studies, in biochemistry, molecular biology or structural biology. An ability to independently determine X-ray crystal structures of proteins is essential. Experience in high-throughput crystallography for drug discovery would be considered an asset.
The position is offered on a fixed term contract of up to two years in the first instance with a starting salary in the range £26,597 to £29,256 p.a. inclusive.
Informal enquires may be made to Dr Richard Bayliss (Tel: +44 (0)20 7153 5557 / Email: [EMAIL PROTECTED]). Please DO NOT send your application to Dr Bayliss; CVs must be submitted in line with the instructions below.
For further particulars and details of how to apply, please visit our website at www.icr.ac.uk. Alternatively you may call our 24 hour recruitment line on 020 7153 5475 quoting reference number C137.
Closing date: 2 May 2008 The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP. This e-mail message is confidential and for use by the addressee only. If the message is received by anyone other than the addressee, please return the message to the sender by replying to it and then delete the message from your computer and network.
