Hi all!
Just want to ask whether some of you has experience with TMAO (or
similar conformation stabilizers) for setting up crystallization
screenings?
Which concentration range would you use? Would you add TMAO to the
protein tube and afterwards add the mixture to the plates?
Just wanted to know your opinion about conformation stabilizers: could
they really help to crystallize multi-domain proteins, supposed to be
"flexible"?
Thank you very much in advance for your attention,
With my best wishes,
Ruben
