Sorry for this very prosaic question:

does anybody have a reference describing the mechanisms of reducing agents (TCEP, DTT, BME, etc.), and in particular the effects of the reactions on pH? I think I can draw a convincing reaction mechanism for myself, but I am not sure theoretically why (or even whether) the pH drops in the presence of reducing agents (although I am pretty sure empirically that it does.) I have looked around a bit, but perhaps have not hit on the right google search terms...

Thanks,

Jacob Keller

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Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.491.2438
cel: 773.608.9185
email: [EMAIL PROTECTED]
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