POSTDOCTORAL POSITION IN STRUCTURAL IMMUNOLOGY
A NIH funded postdoctoral position is available April 1st (not a
joke!) to work on the structural, functional and biophysical
characterization of lipid reactive T cells.
We are looking for a qualified and highly motivated biochemist/
structural biologist with 0-2 years of postdoctoral experience.
Main focus of the project:
1) crystal structure determination of different CD1-glycolipid-TCR
complexes
2) biophysical characterization of the CD1-glycolipid-TCR
interaction, mostly binding kinetic measurements by Surface Plasmon
Resonance.
3) functional characterization of T cell hybridomas (T cell
activation as measured by IL-2 release).
Requirements:
1) Ph.D or an equivalent degree (obviously)
2) experience in cloning (I don't design your primers!), protein
expression (insect cells), purification, crystallization and
structure determination (mainly by MR).
3) ability to work independently but also as part of a team.
4) general interest in immunology.
The structural biology lab is well equipped with state of the art
robotics and imaging systems (Art Robbins Phoenix, Rigaku Desktop
Minstrel), a xray source (Oxford Diffraction Xcalibur PX Ultra) and
access to SSRL for remote data collection.
Applications, including the name an addresses of 2 references should
be directly send to dzaj...@liai.org
Dirk Zajonc, Ph. D.
Assistant Member
Division of Cellular Biology
La Jolla Institute for Allergy & Immunology
9420 Athena Circle
La Jolla, CA 92037
e-mail: dzaj...@liai.org
http://www.liai.org/pages/faculty-zajonc
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The La Jolla Institute for Allergy & Immunology is located in UC San
Diego's Science Research Park and is a world-class facility covering
145,000 square feet. Our space provides an open laboratory setting
that encourages La Jolla Institute for Allergy & Immunology's highly
collaborative research environment. Specialized research rooms are
suited for all aspects of molecular and cellular biology and feature
larger lab areas that can support critical technologies and
infrastructure. These technologies include highly sophisticated
instrumentation for analysis at the atomic, genetic, protein and
cellular levels - all of which are critical to advancing
understanding of immune system disease.
