Dear all,
I have a crystal structure of a protein whose first 40 residues are in a
helical conformation. This helix was found to be bent, with the bend
occurring at residues 27-30, by an angle of roughly 60 deg . We believe
this bend was caused by crystal packing forces as this helix nicely packs
in with the neighboring symmetry related molecules. I was wondering if
anybody has any references of similar cases where conformations have been
altered due to crystal packing.
Thanks to all in advance.
-Shahila
Shahila Mehboob, PhD.
Visiting Research Assistant Professor
Center for Pharmaceutical Biotechnology, M/C870
University of Illinois at Chicago
900 South Ashland Ave.
Chicago, IL 60607
Phone: 312-413-9304 (lab)
Phone: 773-531-5470 (cell)
Email: shah...@uic.edu
