Dear All, I have a question about the occupancy refinement of a ligand. I have a dataset of 2.3 angstrom and the ligand binds in multiple conformations in the active site. My question is if it is possible to tell which orientation(s) has/have the highest occupancy based on occupancy refinement. What is the best way to refine the occupancy?
Thanks, Mariah -- Mariah Jones Department of Biochemistry University of Florida
