On Wed, Feb 18, 2009 at 3:32 PM, Francis E Reyes <francis.re...@colorado.edu
> wrote:
>
> Single isomorphous replacement with anomalous scattering uses two datasets
> that are isomorphous while using the anomalous signal in one (here
> scattering and dispersion are synonymous?). How does SIRAS use the anomalous
> scattering signal that's different than a single wavelength anomalous
> dispersion ?


I'll leave the answering of questions to the experts, but there's an
excellent review from one of the CCP4 study weekends a few years ago that
summarizes most of these methods (and should answer at least the first
question):

http://journals.iucr.org/d/issues/2003/11/00/ba5050/index.html

I found the comparison of Harker diagrams very helpful.

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