Dear All,
Thank you very much for all your suggestions. They are very helpful in my
further refinements. I am adding some more information about the problem:
1) The Z-score is 11.2 and LLG is 125.
2) The model has 390 aa while my structure has about 440 aa.
Please let me know of any further suggestions.
I will try all your suggestions and let you know the updated information about
the refinement.
Best regards,
Sun
________________________________
From: Ho-Leung Ng <hole...@berkeley.edu>
To: CCP4 bulletin board <CCP4BB@jiscmail.ac.uk>; suntang2...@yahoo.com
Sent: Wednesday, March 18, 2009 12:10:29 AM
Subject: Re: How to refine a solution obtained by molecular replacement
I've found CNS's simulated annealing composite omit maps to be
very useful in situations like this to avoid phase bias. RESOLVE's
prime and switch offers similar functionality, but I've had less
experience with it.
ho
UC Berkeley
