The position is available in the group of X-ray crystallography, Department of Cellular Biochemistry (Prof. Reinhard Lührmann).
The project is part of the extensive effort of our department towards understanding the structural basis of the spliceosome function. The spliceosome is a multi-megadalton molecular machine which consists of over 150 proteins and a complex RNA network. This makes it one of the most challenging crystallographic targets that can be imagined. The activities will include recombinant protein isolation, biochemical characterization, crystallization, structure determination and further complementation by biochemical and genetic methods. We have excellent labs for recombinant expression in E.coli and insect cells, wet labs with various chromatography systems, state of the art crystallization facilities, good computational infrastructure and easy access to more synchrotron beamlines. The applicant should have a MSc or a BSc diploma in biochemistry, biophysics or related fields and some research experience in a laboratory. Please send your application, including a CV and a list of referees to Dr. Vlad Pena via e-mail (vp...@gwdg.de). . Vlad Pena, PhD Max Planck Institute for Biophysical Chemistry Department of Cellular Biochemistry X-Ray Crystallography Am Fassberg 11, D-37077 Göttingen, Germany Phone: +49 (0)551 201-1591