Hi, All Suppose I have two proteins A and B, they are structurally homologous, however the sequence identity is only about 20%. A has crystal structure available, so if I want to model protein B, what's the best way to do it? I don't think I can just thread the sequence of B to A structure because the number of residues are different and there might be gaps and insertions in the alignment. Any suggestions of good programs?
Thanks. Rui