When there is a greater-than-10-fold range of prices, as here, it seems that there is unfair business going on. I am no expert on European business law, but I suspect there might be something illegal here.

Jacob Keller

*******************************************
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.491.2438
cel: 773.608.9185
email: j-kell...@northwestern.edu
*******************************************

----- Original Message ----- From: "Mark J. van Raaij" <mark.vanra...@usc.es>
To: <CCP4BB@JISCMAIL.AC.UK>
Sent: Tuesday, July 14, 2009 11:56 AM
Subject: [ccp4bb] Summary IPTG suppliers (mainly Europe)


Current EU IPTG prices in euros, approximate, without tax, delivery or
currency exchange fees. Prices are quoted as to my best knowledge, but
of course may be different when you order at a different time or from
a different place. I do not claim it is complete.

Apollo Scientific (UK): 5 g 18 euros, 25 g 85 euros
Biosynth (Switzerland): 10 g 40 euros, 25 g 89 euros, 50 g 160 euros,
100 g 286 euros
ForMedium (UK): 1 g 9 euros, 5 g 28 euros, 10 g 51 euros, 25 g 118
euros, 100 g 378 euros, 250 g 765 euros
Melford (UK): 1 g 10 euros, 5 g 31 euros, 10 g 56 euros,  25 g 131
euros, 50 g 244 euros, 100 g 450 euros
Nzytech (Portugal): 1 g 28 euros, 5 g 52 euros
Eurogentec (via Cultek): 1 g 21 euros, 5 g 84 euros
Qiagen (via Izasa): 5 g 142 euros
Promega: 50 g 1140 euros, 5 g 181 euros, 1 g 61 euros
Invitrogen: 1 g, 44 euros
Sigma-Aldrich: 5 g 250 euros, 10 g 494 euros

Fermentas was also mentioned at 33 pounds for 5 g, but their web does
not let you see the price unless you register (it also does not
mention Spain in the shipping list, perhaps it has a distributor here
I am unaware of).
It appears UK/Swiss companies are the cheapest, and the UK is in
Europe, although some people seem to think otherwise. Seriously, for
us ordering the UK is as easy as ordering from Spain or other European
countries. I am not sure how easy ordering from Switzerland would be,
I have never tried...
All people give good refs of the supplier used (i.e. absence of
expression problems), except for one person, who only uses Sigma IPTG
after problems with other sources.

Another supplier mentioned without EU distributors was:
Gold BioTechnologies: 25 g 99 USD, 100 g 309 USD, 300g 799 USD

Several people mentioned Studiers auto-induction methods, which avoids
having to use IPTG and gives them better cell density and, in some
cases, more expression of soluble protein.

Thanks to all for their comments and knowledge of companies I had
never heard of and did not find with Google,

Mark




Mark J. van Raaij
Dpto de Bioquímica, Facultad de Farmacia
Universidad de Santiago
15782 Santiago de Compostela
Spain
http://web.usc.es/~vanraaij/

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