Hi Francis, There is an older paper that mentions this idea: Tsao et al, Acta Cryst B48 (1992), 75-88. However, when you look at the paper, small-angle scattering data is not the only thing that was used. In particular, if my memory serves me right, the 60-fold averaging applied to the problem really made all the difference in getting the phases right. The big difference that works to your advantage is that small-angle scattering was not nearly as well developed at the time as it is now. For example, I don't think they could get molecular envelopes in 1992. There is sufficient information available these days that the test could be done (for appropriate systems).
Mark -----Original Message----- From: Francis E Reyes <francis.re...@colorado.edu> To: CCP4BB@JISCMAIL.AC.UK Sent: Mon, Sep 14, 2009 9:47 am Subject: [ccp4bb] Using SAXS data for phasing at mediocre resolution. Hi all? ? I'm looking for anyone who has had (practical) experience using SAXS data to phase 4.2 A crystals. Please email me.? ? FR? ? ---------------------------------------------? Francis Reyes M.Sc.? 215 UCB? University of Colorado at Boulder? ? gpg --keyserver pgp.mit.edu --recv-keys 67BA8D5D? ? 8AE2 F2F4 90F7 9640 28BC 686F 78FD 6669 67BA 8D5D?