Dear all --

Just a short reminder that we are looking for talented and motivated persons to apply for the following post-doctoral position. The deadline is coming closer now ! I would like to add as well that knowledge of Japanese is not a requirement (although the successful candidate might enjoy eating sushi...).

Kind regards.

-- Leo --

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Post-doctoral position. Structural Biology Research Center, Tsukuba, Japan

[Closing date]
All documents should arrive at the latest on the 29th of January 2010.

[Job description]
The Structural Biology Research Center offers a state of the art international and stimulating environment for research in a multi- disciplinary framework. Notably, molecular structural biology research in the field of intracellular transport and posttranslational modification including ubiquitylation is vigorously pursued and tightly linked with development and operation of synchrotron protein crystallography beamlines at the Photon Factory. We are looking for an enthusiastic post-doctoral fellow to work on proteins involved in intracellular transport and posttranslational modification processes. Some of the recent publications on the relevant research areas include:

• Rahighi S, Ikeda F, Kawasaki M et al. (2009) Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell 136:1098-1109

• Dikic I, Wakatsuki S, Walters KJ (2009) Ubiquitin-binding domains - from structures to functions. Nat Rev Mol Cell Biol 10:659-671

• Chavas LM, Ihara K, Kawasaki M et al (2008) Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/ Slp2-a. Structure. 16:1468-77

• Kudo N, Kimagai K, Tomishige N et al. (2008) Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide. Proc Natl Acad Sci U S A. 105:488-93

• Hirano S, Suzuki N, Slagsvold T et al. (2006) Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain. Nat Struc Mol Biol. 13:1031-2

More information can be obtained on the following website: http:// pfweis.kek.jp/eng/index.html.

[Qualifications and Experience]
Motivated applicants should have a Ph.D. in a relevant field. Working experience in molecular biology and biochemistry is required. Previous experience with large-scale protein expression, purification, crystallization, structure determination, and structure analysis will be considered advantageous. Experience in the field of intracellular transport or posttranslational modifications would be a plus.

[Contract]
The contract will be issued on a yearly basis with possible extensions. The future employee will benefit from the social insurance, travel allowance and assistance with housing in accordance with the institute restrictions.

[Start of the contract]
Ideally, the contract will start from April 2010. Nevertheless, the exact starting date stays open to discussion with the candidate.

[Applications]
To apply, please send a cover letter, CV (in English) with a summary of your previous work and research skills (A4, 1-2 sheets), reprints of your key papers, your research aspirations (A4, 1-2 sheets), and the contact information of two professional references. When possible, the required documents should be submitted by e-mail.

[Inquiries and contact information]
When possible, the candidates should apply by e-mail. Please address all communications to Mrs. Ishikawa Gin (gin.ishik...@kek.jp).

Prof. Soichi Wakatsuki
Structural Biology Research Center,
Photon Factory, Institute of Materials Structure Science,
High Energy Accelerator Research Organization (KEK).
1-1 Oho, Tsukuba, Ibaraki, 305-0801, Japan.
Tel: +81-(0)29-879-6178 - Fax: +81-(0)29-879-6179
e-mail: soichi.wakats...@kek.jp

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Chavas Leonard, Ph.D.
Assistant Professor
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Structural Biology Research Center
Photon Factory
High Energy Research Organization (KEK)
305-0801 Tsukuba Oho 1-1
Japan
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Tel: +81(0)29-864-5642 (4901)
Fax: +81(0)29-864-2801
e-mail: leonard.cha...@kek.jp
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Science Advisory Board (BIT Life Sciences)
Editorial Board (JAA)
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http://pfweis.kek.jp/~leo

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