Hi, Similar problem occured even in CCP4-6.1.0 in our case. So, we used to take the phaser output model and do rigid body refinement with REFMAC and see the density (in coot), which normally much better than output from PHASER mtz. I am not sure whether it is for case to case or it is general problem?
-Karthik > Hi , > I just switched to ccp4-6.1.3 and ran the phaser which is bundled > with the ccp4-6.1.3 release. After molecular replacement I get a > pretty good solution (TFZ 59.2) and output pdb and mtz files. > I am then looking at the maps from the phaser output mtz i.e the FWT , > PHWT map and the FWT PHIC map . Both maps look very crappy and look > like noise. I tried the fft inside of coot and separately as a FFT > inside ccp4 and these maps look bad. So the FWT PHWT calc seem to be > off. > > However , if I take the phaser solution output model and do the sigmaa > myself. The map looks normal and sensible. > > It seems like phaser inside of ccp4-6.1.3 is not generating the output > mtz correctly . > Anyone else seeing this or is there something wrong with my setup. > > > Hari > >
