American Crystallographic Association, Inc
2010 Annual Meeting
Chicago, IL July 24-29, 2010
www.amercrystalassn.org/content/pages/2010-meeting
Abstract Submission Deadline - March 31, 2010
Student & Young Scientist Travel Grant applications: March 31
Special Hotel Discount rate: April 30
Advance/lower registration: May 31
Session Name: 01.04 Structural Enzymology: Mechanistic (BioMac)
Day: Thursday morning July 29, 2010
Session Chair: Allen M. Orville, Brookhaven National Lab
Macromolecular crystal structures of ligand complexes or reactive intermediates provide valuable mechanistic insight, but for which the crystallographers often find themselves interpreting mystery density within the data. Thus, the talks and posters in this session are intended to highlight crystal structures and the use of techniques that provide strong correlation(s) to the proposed reaction mechanism. This will likely include important correlations with complementary kinetic and/or spectroscopic techniques. Taken together, the multidisciplinary data provides compelling insights into the proposed reaction mechanism that an individual method has difficulty supporting in isolation.
Three invited speakers will be selected from the abstracts submitted for the session.
They will complement the three confirmed speakers:
Dr. Brian G. Fox, University of Wisconsin, Madison, WI, will present new insights into the reaction cycle of diiron hydroxylase-effector protein complexes.
Dr. George Richter-Addo, University of Oklahoma, Norman, OK, will discuss recent work on the photochemistry of heme-based reactions with single-crystal spectroscopy and x-ray diffraction.
Dr. Paul R. Carey, Case Western Reserve University, Cleveland, OH, is a pioneer in single-crystal Raman microspectroscopy with applications in RNA and enzyme-based catalysis.
Sincerely,
AMO
Allen M. Orville, Ph.D.
Biology Department
Brookhaven National Laboratory
Upton, NY 11973-5000
e-mail: am...@bnl.gov
phone 631-344-4739
fax 631-344-2741
http://www.bnl.gov/biology/People/Orville.asp
