Hi everyone, I am in the process of refining my structure. I have built almost the whole protein. Now its time to add waters. Should I do refinement in refmac5 with (adding waters running coot) or should I use Arp/wArp waters or both?. I have 2.15 Angs near data and about 1200 residues. Does it matter which program I use to add water? Is there something specific I should look for? I apologise in advance if this question has already been asked before.
Thanks, Ivan
