Dear zq deng, The standard method, I dare say, in such a case is micro seeding:
reduce the precipitant to a concentration so that you just do not get crystals any more, wait until the drop equilibrates (about one day in the case your precipitant is a salt, up to 5-7 days for high MW PEGs), then use a cat's whisker for micro seeding into that drop. Well, that's micro seeding in a nut shell. Tim On Thu, May 06, 2010 at 04:03:46PM +0800, zq deng wrote: > hello,everybody . due to excess nucleation,I often get many tiny crystals > instead of few,large crystals.i wana optimize the condition, does anyone > have adivce about this? > > Best regards. -- -- Tim Gruene Institut fuer anorganische Chemie Tammannstr. 4 D-37077 Goettingen GPG Key ID = A46BEE1A
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