Dear all, I am wondering if there are publications, where it is shown that a ligand/substrate was not able to bind in one crystal form of a protein, but was found in another crystal form. In other words: is there a case where the crystal packing interactions are proofed to be responsible for non-binding of a substrate?
Thanks for any hints, Stefanie Dr. Stefanie Freitag-Pohl Durham University Chemistry Dept South Road Durham. DH1 3LE Tel: 0191 3342143 Email: stefanie.freitag-p...@durham.ac.uk