Actually I cut a small domain from the well-defined structure (just for a test). The missing part showed in 2mFo-DFc map but not in both mFo and Fo maps, and the mFo and Fo maps are so close so that I wonder whether figure of merit generated by SIGMAA helps or not in this situation...
Best Regards, Hailiang > On Tue, 2010-08-31 at 13:15 -0400, Hailiang Zhang wrote: >> Is the difference >> between mFo and Fo maps supposed to be very small? > > For an essentially correct model, yes. The major advantage of (2mFo-DFc) > maps is suppression of model bias, so if you don't see much difference > then your model is very well refined. For illustration, introduce a > systematic error on purpose and see which map gives you better result. > > -- > "I'd jump in myself, if I weren't so good at whistling." > Julian, King of Lemurs > >