Dear All,
I'm looking for a free program that I can use to measure the geometric
surface complementarity of protein-protein interfaces. I have created
inhibitor mutants that possess different binding affinities to their
cognate enzyme and it would be very helpful if I can quantify the shape
complementarity of the protein/protein interfaces. The complexes of
inhibitors and enzyme crystal structures have been solved at high
resolution (~1.4A). Sincere thanks in advance and hope to hear from you
soon.
Kind regards,
Mohd Salameh
