In June 1999, staff of the Macromolecular Structure Database (MSD; nowadays known as the Protein Data Bank in Europe, http://pdbe.org/) at the European Bioinformatics Institute (EMBL-EBI; http://www.ebi.ac.uk/) began annotating PDB entries. Now, eleven years later, PDBe has annotated its 10,000th structure, 2YF6 (http://pdbe.org/2yf6). This structure is of a chicken MHC/peptide complex and was determined in the group of Susan Lea at the University of Oxford.

You can read more about this milestone in the Wellcome Trust blog at http://wellcometrust.wordpress.com/2011/04/20/10000th-structure-curated-by-the-protein-data-bank-in-europe/

This month's episode of Quips is also dedicated to 2YF6 - see http://www.ebi.ac.uk/pdbe-apps/quips?story=MHCstory

For some early history of MSD/PDBe, see http://www.riethoven.org/BioInformer/newsletter/archives/6/msd.html

We are grateful to all the structural biologists who have deposited their structures with PDBe and look forward to annotating the next 10,000 entries!

--Gerard

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Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk ..................... pdbe.org
Secretary: Pauline Haslam  pdbe_ad...@ebi.ac.uk

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