On Mon, May 23, 2011 at 1:02 PM, Hailiang Zhang <zhan...@umbc.edu> wrote:
> I have a preliminary question. I understand Rfree reflection sets are > never used during automatic refinement, but, when generating the real > space density maps, do we have to exclude Rfree columns? Any references > will also be greatly appreciated! > If you are going to run overall real-space refinement on the structure, you should absolutely exclude the test set reflections from the map. If you are only going to run local refinement of small parts of the model in Coot or equivalent, it's debatable - in practice, I think most people/programs leave them in. -Nat
