On 30 Jun 2011, at 01:42, Michael Thompson wrote:

> the introduction of a disulfide can create artificial "crystal contacts," 
> which also aid in crystallization

Another example of this is described here:

The structural and energetic basis for high selectivity in a high-affinity 
protein-protein interaction.
Meenan NA, Sharma A, Fleishman SJ, Macdonald CJ, Morel B, Boetzel R, Moore GR, 
Baker D, Kleanthous C.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10080-5. 


Huw 

--
Dr Huw Jenkins
Astbury Centre for Structural Molecular Biology
University of Leeds

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