This brings up a philosophical caveat that one should be very careful about labeling one set of potential results "negative" and another "positive" before even doing the experiment, because its all too easy to see what you hoped to see even if it was only marginally there.
The best experimentalists rig things so that something will be learned from any possible result. Of course, in this light, crystallization is a really stupid experiment. And by the time I'm really convinced that we're getting nowhere crystallizing something, I'm too demoralized to bother writing up all the ways to not crystallize it. Phoebe ===================================== Phoebe A. Rice Dept. of Biochemistry & Molecular Biology The University of Chicago phone 773 834 1723 http://bmb.bsd.uchicago.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=123 http://www.rsc.org/shop/books/2008/9780854042722.asp ---- Original message ---- >Date: Mon, 11 Jul 2011 16:35:31 +0530 >From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> (on behalf of Partha >Chakrabarti <ppc...@gmail.com>) >Subject: Re: [ccp4bb] Fwd: Could Biological Negative Results be published? >To: CCP4BB@JISCMAIL.AC.UK > > What if the negative results contradict some recent > papers in big journals? Would the PI risk his / her > contacts & connections? Of course for the PhD > student or postdoc, it matters a lot to get it > 'published'.. > > On Mon, Jul 11, 2011 at 4:27 PM, Bosch, Juergen > <jubo...@jhsph.edu> wrote: > > http://www.jnrbm.com/ > Might this be what you are looking for ? > Jürgen > ...................... > Jürgen Bosch > Johns Hopkins Bloomberg School of Public Health > Department of Biochemistry & Molecular Biology > Johns Hopkins Malaria Research Institute > 615 North Wolfe Street, W8708 > Baltimore, MD 21205 > Phone: +1-410-614-4742 > Lab: +1-410-614-4894 > Fax: +1-410-955-3655 > http://web.mac.com/bosch_lab/ > On Jul 11, 2011, at 6:03 AM, F.Xavier Gomis-Rüth > wrote: > > Dear CCP4ers, > I think this is a very interesting initiative > and it could potentially lead to a discussion > within the board. > Best, > Xavier > > -------- Mensaje original -------- > > Asunto: Could Biological Negative Results be > published? > Fecha: Sun, 10 Jul 2011 21:39:52 -0500 > De: David Alcantara > <listmas...@mail.arjournals.com> > Para: f...@ibmb.csic.es > > Dear colleague, > > As you are well aware it is common in our field that many of our > endeavors do not lead to the results we want or expect. Numerous tests > and experiments have outcomes that we share with our immediate > colleagues during informal meetings, but that we are not considering > material for publication. As a result a wealth of information is never > brought to the attention of the greater public, which is not only > unfortunate, but also has others repeating similar studies to produce > the same negative results. Not only are a lot of resources like time > and money wasted in this way, but it also leads to frustration that > could have been prevented if only the scientists would have been aware > of the negative results of earlier studies. > > My name is David Alcantara and, on behalf of our editorial board, > I’d like to invite you to submit your articles to The All Results > Journals: Biology, a new journal that focuses on publishing the grey > literature that has never been published. It is our goal to compile > and publish those experiments that led to negative results or to > outcomes that were not expected and were not before considered for > publication. We of The All Results Journals feel that it is equally > important to publish these results together with interpretations of > the scientists involved and in this way offer a solution to the > problem that publication bias is causing, because of a strong emphasis > on positive results. > > The All Results Journals:Biol is a peer-reviewed journal dedicated to > publishing articles with negative results and outcomes that were not > expected and were not before considered for publication in all areas > of Biology (pure and applied). The Journal is TOTAL Open Access (no > fees to publish and read) and is being indexed by well-known > scientific databases such as Web of Knowledge, Scirus, and Pubmed This > will assure maximum exposure of your articles. > > We expect to publish articles within four to six weeks of submission, > and our award-winning OJS Publications Web Editions Platform will > showcase your important findings to the international scientific > community. > > Please check our info for authors to submit your articles at: > > http://www.arjournals.com/ojs/index.php?journal=Biol&page=information&op=authors > <http://arjournals.com/ojs/index.php?journal=Biol&page=information&op=authors> > > Thank you very much for your time and we look forward to hearing from > you.. > > With kind regards, > > David Alcantara > > -- > David Alcantara, Ph.D > Managing Editor > alcant...@arjournals.com > Phone: 001 617 575 9152 > The All Results Journals:Biol (ISSN: 2172-4784) > http://www.arjournals.com/ojs/index.php?journal=Biol > Follow us on > http://www.facebook.com/pages/The-All-Results-Journals/53410901726 > --- > > This e-mail is from The All Results Journals. The e-mail and any files > transmitted with it are confidential and intended solely for the use > of the individual or entity to whom they are addressed. Any > unauthorized dissemination or copying of this e-mail or its > attachments, and any use or disclosure of any information contained in > them, is strictly prohibited and may be illegal. If you have received > this e-mail in error, please notify or telephone and delete it from > your system. > > -- > If you do not want to receive any more e-mails from us visit, > http://mail.arjournals.com/?p=unsubscribe&uid=7f58f771c3b6364a657dc5f086f8962f > > > > > -- > Powered by PHPlist, www.phplist.com --
