Dear All
I was working two domain protein and i have an hexagonal look like crystals from additive screen, now i am facing problem these crystal are growing in 2 minutes even in cold room even at lower protein concentration @2mg/ml . and i have an smeary data of 7 Å, and we thinking one domain might be flexible and other is stable is there anyway to increase the crystal packing .... Any suggestions are welcome. Eswar Reddy