This is very common among the small GTP-binding proteins of the Ras superfamily. For an interesting analysis (although doubtless there are lots of more recent examples) you might look at: Corbett and Alber, TIBS 26 (12) 710-716 (2001)
Evette S. Radisky, Ph.D. Assistant Professor Mayo Clinic Cancer Center Griffin Cancer Research Building, Rm 310 4500 San Pablo Road Jacksonville, FL 32224 (904) 953-6372 -----Original Message----- From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Yamei Yu Sent: Tuesday, August 23, 2011 9:45 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Is there a protein that it could interact with different proteins by the same part? HI all, We know one protein can interact with different partners by different domains or different parts. Is there a protein that it could interact with different proteins by the same part (maybe the same part but in different conformations?)? Thank you in advance!! yamei