The Berger laboratory at the European Molecular Biology Laboratory (EMBL)
Grenoble, France seeks to recruit an outstanding postdoctoral scientist in
structural biology with a research focus directed towards the structure of
macromolecular assemblies. The major theme within the group is the structural
molecular biology of multiprotein complexes in human gene expression. For this
purpose, we are also very active in the development and implementation of
advanced recombinant expression technologies (Fitzgerald et al. Nat. Methods
2006; Bieniossek et al. Nat. Methods 2009; Kriz et al. Nat. Communications
2010). Notably our MultiBac technology is our unique asset for producing large
multisubunit transcription factors in the quality and quantity required for
structural analyses (Berger et al. Nat. Biotechnol. 2004, Imasaki et al. Nature
2011). A number of highly purified complexes are available in the laboratory.
Information about our work can be obtained from
http://www.embl.fr/research/unit/berger/index.html.
This position requires a Ph.D. in biochemistry or a related field, with a
strong background in molecular biology and protein biochemistry. The applicant
has experience in structure determination projects from start to finish,
experience in expressing and purifying protein complexes and /or Electron
Microcopy or X-ray crystallography are advantageous. The candidate is a highly
motivated individual who enjoys working as part of a collaborative and
multidisciplinary, dynamic and interactive team.
The laboratory is excellently situated in the structural biology environment at
the Polygone Scientifique in Grenoble. Access to our Eukaryotic Expression
Facility (EEF), synchrotron X-ray radiation (ESRF), modern biophysical
instrumentation (surface plasmon resonance, dynamic light scattering,
isothermal calorimetry, analytical ultracentrifugation), and to electron
microscopy is provided. Complementary collaborations with leading laboratories
in the field are in place.
The position is available immediately and funded for 2 years. It can be
extended dependent on performance.
To apply please send your CV, a statement of research interests, and names
(including email address) of at least two referees by email to Dr. Imre Berger
(iber...@embl.fr). Applications will be accepted until the position is filled.
