Hi all,
As you may recall, the Protein Data Bank in Europe (PDBe; pdbe.org) regularly
produces Quips, short stories about QUite Interesting Pdb Structures
(pdbe.org/quips). Quips address biologically interesting aspects of one or
more PDB entries, coupled with interactive graphics views and often a
mini-tutorial or suggestions for further exploration using PDBe services and
resources.
Today another Quips episode was released. It is about autotaxins,
physiologically important proteins that are pursued as anti-cancer drug
targets. This Quips was developed together with scientists from the
Netherlands Cancer Institute (Tassos Perrakis and Wouter Moolenaar) to
accompany their review paper in Nature Reviews Molecular Cell Biology on
autotaxin structure and function that was also published today.
- For the Quips story ("Autotaxins: inhibiting a greasy pocket"), go to:
http://pdbe.org/quips?story=Autotaxin
- For the review paper ("Insights into autotaxin: how to produce and present a
lipid mediator"), go to:
http://www.nature.com/nrm/journal/vaop/ncurrent/full/nrm3188.html
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If you have an interesting structure whose story you would like to tell (with
our help) in the form of a Quips episode, please contact us at p...@ebi.ac.uk
--Gerard
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Gerard J. Kleywegt, PDBe, EMBL-EBI, Hinxton, UK
ger...@ebi.ac.uk ..................... pdbe.org
Secretary: Pauline Haslam pdbe_ad...@ebi.ac.uk
