Dear all,

I am trying to refine a structure with two domains. The electron
density of one domain is reasonable, but that of the other domain is
poor. So, I am wondering whether the refinement by Phenix or Refmac
can be done locally with two parts, the first domain is refined with
normal restrains, the second domain is refined by rigid body and group
B?

Thank you so much!

Best,
Zhiyi

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