Dear all,
I have some questions about the correct protocol for refinement of twinned data (0.46)

1- How do I ensure that my Rfree set is generated properly?

2-I noticed that if I enable intensity based twin refinement, refmac estimates the correct twin fraction law -h,-k,h+l. But for subsequent refinement rounds should I keep using the raw intensity mtz file or
the newly generated mtz with PHIC and FOM information?

Thank you
--
Yuri Pompeu

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