A 2 year postdoctoral position with support from the French National
Research Agency (ANR) is available to study regulatory mechanisms of
BMP-1/tolloid like proteinases ((BTPs; also known as procollagen
C-proteinases) which are enzymes implicated in a number of key events
during tissue morphogenesis and tissue repair. The research project
proposed aims at a better understanding of the mechanism by which
specific enhancer proteins regulate BTP activity, by solving the 3D
structure of the complex of the substrate:enhancer complex.
Our studies involve a multidisciplinary approach, which combines
molecular- and structural biology along with classical biochemical
procedures.
A Ph.D. in biochemistry or biophysics, and a solid experience in
crystallization and X-ray structure determination are required.
Background knowledge in protein expression and purification is highly
desirable.
Salary in the range 30-35 k€, depending on experience.
The position is immediately available (application deadline December 15,
2011) and interested candidates should send their CV, a letter of
interest and contact information of 3 references to Dr. Nushin Aghajari;
n.aghaj...@ibcp.fr and Dr. David Hulmes; d.hul...@ibcp.fr.
