Dear all,
A post-doctoral position is available in the Structural Biology and
Biophysics group at Pfizer's research labs in Groton, Connecticut (USA).
To apply, please go to www.pfizer.com/careers and search for job ID
959727.
Job Focus
The successful candidate for this position will join Groton Structural
Biology and Biophysics (SB&B), a multi-disciplinary group with
well-established expertise in molecular biology, protein biochemistry,
biological mass spectrometry, NMR, biophysics, crystallography &
computational sciences. Our mission is to provide integrated molecular
insights into drug target mechanism and target-ligand interactions to
impact discovery efforts across important therapeutic areas, such as
Immunology & Autoimmune Diseases, Inflammation & Remodeling,
Neuroscience, Cardiovascular, Metabolic & Endocrine Diseases and
Oncology.
As a Postdoctoral Scientist - Protein Crystallography, you will be able
to use your creativity, energy and expertise to contribute to cutting
edge science and drug discovery through structural studies of a few
novel multi-domain proteins from our rich portfolio of exciting
therapeutic targets. You will drive the progression of these projects
through protein expression, purification, characterization,
crystallization and structural analysis in collaboration with other
scientists in our multidisciplinary teams. You will have the opportunity
to explore a wide range of biophysical techniques to solve your
scientific problems, and learn from scientific experts in these areas.
You will also have the opportunity to develop a broad understanding of
other disciplines involved in drug discovery. You will be highly
encouraged publish in peer reviewed journals and present your results at
international conferences.
Responsibilities
- Design and execute experiments in construct design, protein
expression, purification, characterization, crystallization, structural
solution using de novo methods.
- Analysis of relevant data and literature to extract novel structural
insights and experimental design ideas
- Collaborative efforts with academic labs will be considered as well
Qualifications
- Doctoral degree in Biochemistry, Molecular Biology, Chemistry or
related field
- Established track record applying innovative methods to drive project
success throughout the gene-to-structure process
Prior Experience:
- 0-2 years of postdoctoral experience
- Knowledge of crystallography theories and applications
- Breadth of knowledge in related fields
- Strong oral and written presentation skills
- Proven ability to design and conduct experiments from protein
expression to structure solution, leading to publication in reputable
journals
- Familiar with protein characterization, biophysical, computational
techniques and has a passion for solving tough scientific problems using
broad and creative thinking and experiments
- Strong interpersonal and communication skills
