Structural and biophysical methods for biological macromolecules in solution
EMBO Global Exchange Lecture Course
29 November?6 December 2012 Hyderabad, India
http://events.embo.org/12-macromolecule/index.html
The main objective of the Course is to teach the young PhD students
and postdocs
from all areas of biology the methods applicable to study biological
macromolecules in solution. We aim at a comprehensive coverage of the
field including the major structural and biophysical techniques
employed for the characterization of high and low resolution structure
and structural transitions, macromolecular complex formation, protein
folding and stability, protein-protein and protein-ligand interactions
and enzymatic mechanisms. The Course will include lectures on
small-angle X-ray and neutron scattering (SAXS/SANS), nuclear magnetic
resonance (NMR), static and dynamic light scattering (SLS/DLS),
analytical ultracentrifugation (AUC), surface plasmon resonance (SPR),
differential and isothermal calorimetry (DSC/ITC) and spectroscopic
approaches. Bioinformatic tools to analyze protein-protein
interactions will also be considered, and the joint use of the
solution characterization methods with the major non-solution
structural techniques,
macromolecular crystallography (MX), electron microscopy (EM), mass
spectrometry (MS) and with the in situ methods will be covered.
Special attention will be paid to interdisciplinary approaches, where
the synergistic use of complementary techniques leads to a
comprehensive description of macromolecular systems.
From the Indian side, the Course will be co-organized by the Centre
for Cellular and Molecular Biology (CCMB), Hyderabad, and the Tata
Institute of Fundamental Research (TIFR), Mumbai. The course will be
held at CCMB in Hyderabad immediately following an International
meeting on biology (25-27 November 2012), commemorating 25 years of
moving into the current CCMB R&D complex.
A maximum of 40 participants will be selected to attend the course.
No registration fee will be requested from the academic participants.
Applicants from industry are expected to pay a 1000 Euro fee.
The Course is oriented towards applicants active in structural biology,
mostly late Ph.D. students and early post-docs but more senior scientists,
depending on circumstances, could also participate.
Students working in India or Indian students working abroad will be
given preference but all applications are welcome at
http://events.embo.org/12-macromolecule/application.html
Application deadline for the Course: September, 17th, 2012