Greetings everyone. I'd like to call your attention to the following postdoc opportunity:
Postdoctoral research opportunity in antibiotic drug resistance Applications are invited for a postdoctoral position to study the structural biology of proteins and enzymes that comprise AmpC beta-lactamase induction pathway. Beta-lactam antibiotics act to disrupt bacterial cell wall metabolism. Numerous bacterial pathogens respond to this disruption by inducing the expression of AmpC beta-lactamase. AmpC is of considerable clinical concern since it confers broad-spectrum resistance against beta-lactams. We focus on understanding the structural biology of bacterial cell wall metabolism and the development small molecule based strategies to block AmpC gene expression during antibiotic therapy. Additional information about our research and recent publications in the area can be found at: http://home.cc.umanitoba.ca/~bmark/Welcome.html We seek an enthusiastic, hard working individual who holds a PhD in biochemistry or related field. Candidates should have a strong background in molecular biology and protein X-ray crystallography. Experience in membrane protein crystallography would be an asset. We are located in the Department of Microbiology, University of Manitoba, Winnipeg, Canada. The laboratory offers state-of-the-art X-ray instrumentation (Rigaku), crystallization robotics (Art Robbins), and on-going user access to the Canadian Light Source Synchrotron via mail-in service, remote robotics, or in-person visits. The University of Manitoba (http://umanitoba.ca/) is the largest University in the province (over 30,000 students, faculty, and staff) and hosts a dynamic biomedical research community. Winnipeg is a vibrant, multicultural city with numerous cultural events and festivals (http://www.destinationwinnipeg.ca/). Salary will be in accordance with the Canadian Institutes of Health Research (CIHR) (http://www.cihr.ca/ ) standards. The position also includes a University benefits package. All qualified candidates are encouraged to apply. Please direct inquiries, including a cover letter, brief description of your career goals and CV (including names of three referees) to Brian Mark at the following email address: brian.m...@ad.umanitoba.ca<mailto:brian.m...@ad.umanitoba.ca> ========================= Brian Mark, MSc, PhD Associate Professor Manitoba Research Chair in Structural Biology Department of Microbiology & Department of Biochemistry and Medical Genetics Mailing/Courier address: Department of Microbiology Rm 418 Buller Building University of Manitoba 45 Chancellor's Circle Winnipeg, Manitoba CANADA R3T 2N2 Phone (204) 480-1430 Fax (204) 474-7603 Web: http://home.cc.umanitoba.ca/~bmark/Welcome.html
