On Sat, Jun 22, 2013 at 1:04 PM, Douglas Theobald <dtheob...@brandeis.edu>wrote:

> Feel free to prove me wrong --- can you derive Ispot-Iback, as an estimate
> of Itrue, from anything besides a Gaussian?
>

OK, I'll prove myself wrong.   Ispot-Iback can be derived as an estimate of
Itrue, even when Ispot<Iback, assuming a logistic model, laplace model, and
probably others that allow negative values.  I doubt anyone cares about
these more exotic models, the point is that to get Ispot-Iback as an
estimate of Itrue when Ispot<Iback requires a non-physical model that
allows negative photon counts and intensities.

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