On Sat, Jun 22, 2013 at 1:04 PM, Douglas Theobald <dtheob...@brandeis.edu>wrote:
> Feel free to prove me wrong --- can you derive Ispot-Iback, as an estimate > of Itrue, from anything besides a Gaussian? > OK, I'll prove myself wrong. Ispot-Iback can be derived as an estimate of Itrue, even when Ispot<Iback, assuming a logistic model, laplace model, and probably others that allow negative values. I doubt anyone cares about these more exotic models, the point is that to get Ispot-Iback as an estimate of Itrue when Ispot<Iback requires a non-physical model that allows negative photon counts and intensities.