Postdoctoral Fellow in Structural Virology Institute for Molecular Virology
University of Minnesota‐Twin Cities Minneapolis, MN 55455 Web: www.virology.umn.edu Description A Postdoctoral Fellow is being sought for a collaboration involving the application of cryo‐electron tomography (cryo‐ET) of human T‐cell leukemia virus particles. This is a collaborative research project between the laboratories of Profs. Wei Zhang, Joachim Mueller and Louis Mansky. Scientists recruited will join a strongly interactive, collaborative and collegial research environment. Minneapolis is a dynamic and progressive city with outstanding cultural attractions and a high standard of living. Skills Candidates are expected to have a strong background in (cryo‐)electron microscopy /tomography/image processing and analysis or other structural biology techniques such as X‐ray crystallography or NMR spectroscopy. Experience in molecular and cell biology/biochemistry/molecular virology is a plus. Resources The cryo‐ET data collection will be performed using the TF30 Tecnai FEG TEM, which is housed in the Characterization Facility ( http://www.charfac.umn.edu). The microscope includes a Gatan image filter for electron energy loss spectroscopy and energy filtered imaging, as well as high angle annular dark field detector for Z‐contrast imaging. Xplore3D, SerialEM, UCSF tomo and Amira software are available for TEM/STEM Tomography. The facility is also equipped with a FEI vitrobot, Tecnai Bio‐Twin Spirit TEM, FEI iCorr, high pressure freezing/freeze‐substitution instruments, cryo‐microtome and FEG‐SEMs. The facility offers excellent training opportunities for electron microscopy related techniques. The University of Minnesota’s Supercomputing Institute (http://www.msi.umn.edu) offers an excellent computation environment. Contacts Inquiries and applications should be sent to: zhang...@umn.edu or man...@umn.edu
