Dear Jacob, 6 phosphogluconate dehydrogenase :- See Chen et al 2010 J Struct Biol 169,25-35 and for which enzyme there has been a longstanding interest in the protein dynamics and studies linking with diffuse X-ray scattering: see Biochem Soc Trans (1986) 14, 653-655. Best wishes, John
Prof John R Helliwell DSc On 27 Feb 2014, at 19:43, "Keller, Jacob" <kell...@janelia.hhmi.org> wrote: > Dear Crystallographers, > > Does anyone know of good examples of large, reversible conformational changes > occurring between ligand-free and -bound states? Could also be a non-relevant > molecule binding, like sulfate or something inducing dubiously -relevant > changes. I already know of the calmodulin and periplasmic binding protein > families, but does anyone know of others out there? > > All the best, > > Jacob Keller > > ******************************************* > Jacob Pearson Keller, PhD > Looger Lab/HHMI Janelia Farms Research Campus > 19700 Helix Dr, Ashburn, VA 20147 > email: kell...@janelia.hhmi.org > *******************************************