AstraZeneca Mölndal have a Post-Doc position available entitled; Structure and function of pseudokinase KSR's allosteric activation of MEK/B-Raf in RAS-ERK signalling
Accountabilities/Responsibilities * Conduct structural studies of the KSR complex in the RAS-ERK signalling pathway * Rational design of protein constructs in order to purify components of the signaling ternary complex * Work closely with associated Post-Doc assigned to study ATP kinetic studies of KSR * Communicate results both within AstraZeneca and externally at meetings and through publications * Work collaboratively with experts internally within Discovery Sciences Structure and Biophysics and externally with academic co-supervisors Minimum Requirements - Education and Experience * PhD in Protein crystallography * Baculovirus protein expression and purification * Oncology knowledge with understanding of cellular signalling and/or tumour metabolism * Strong interpersonal, organizational and communication skills * Proven ability to independently design and execute incisive experiments and interpret results For more information and to apply, search the AstraZeneca Careers page or click the link below http://gs.globalsuccessor.com/fe/tpl_astrazenecaV2.asp?s=4A515F4E5A565B1A&jobid=60868,9821028740&key=33192595&c=726187021465&pagestamp=seiymcjizvmahfworb Main responsible Paul Wan, Reagents and Assay Development, Discovery Sciences paul....@astrazeneca.com<mailto:paul....@astrazeneca.com> _____________________________________________________________________________________________ Patrik Johansson Associate Principal Scientist AstraZeneca, R&D | Discovery Sciences Pepparedsleden 1, 43183 Mölndal, SWEDEN P +46 31 70 64570, F +46 31 77 63792 -------------------------------------------------------------------------- Confidentiality Notice: This message is private and may contain confidential and proprietary information. If you have received this message in error, please notify us and remove it from your system and note that you must not copy, distribute or take any action in reliance on it. Any unauthorized use or disclosure of the contents of this message is not permitted and may be unlawful.
