The Stuckey Lab in the Life Sciences Institute at the University of Michigan, Ann Arbor campus has two jobs available. Please redistribute these postings however you see fit. Visit umjobs.org for additional information and to apply. Research Lab Specialist Intermediate\Associate <http://umjobs.org/job_detail/97239/research_lab_specialist_intermediateassociate> Job Opening # 97239
The Center for Structural Biology, within the Life Sciences Institute at the University of Michigan, seeks an experienced crystallographer to advance the research objectives of principal investigators in a wide variety of basic science fields and drug development. The Center includes: - A high-throughput cloning and expression laboratory for protein engineering - Protein expression and purification facilities for small- and large-scale protein production - Macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules - X-ray facilities with membership access to high energy synchotron radiation (LS-CAT beam-lines at the Argonne National Laboratory) Staff scientists in the center will work under the direction of Jeanne A. Stuckey, Ph.D, Managing Director of CSB and Research Associate Professor, and work in collaboration with members of her lab and researchers who use the facilities. The successful candidate will apply their energy and expertise to cutting edge science and drug discovery by: - Designing and executing experiments in collaboration with others. - Working in an independent manner. - Aid in coordinating and managing projects on schedule - Maintain clear laboratory notebooks, perform quantitative analyses, and communicate findings through reports and summaries. - Provide detailed documentation so experiments can be replicated. - Follow laboratory best practices for safety and quality. - Being an excellent & proactive communicator, both verbally in writing. - Carrying out innovative research resulting in co- and lead-authored publications on structures of therapeutic and biological importance. - Facilitating the utilization of protein structures by providing expert interpretation in order to enhance the design efforts of the medicinal and computational chemists. - Executing your grasp of modern cloning, expression and purification methodologies. - Developing novel crystallization techniques. - Performing crystallization screens. - Solving structures. RESEARCH FELLOW <http://umjobs.org/job_detail/97198/research_fellow>Job Opening # 97198 The Center for Structural Biology, within the Life Sciences Institute at the University of Michigan, seeks a post-doctoral candidate with crystallography experience, who is interested in developing cutting edge purification and crystallization technologies for RNA and RNA-Protein complexes. The Center for Structural Biology acts as the structural biology core for the Center for HIV RNA Studies (CRNA), which is a large consortium of researchers across the nation focusing on the structures, dynamics, interactions, and mechanisms of action of the HIV-1 RNA during the late phase of viral replication. Funding for these studies is provided by the National Institutes of General Medical Sciences, National Institutes of Health. The Center for Structural Biology includes: - A high-throughput cloning and expression laboratory for protein engineering - Protein expression and purification facilities for small- and large-scale protein production - Macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules - X-ray facilities with membership access to high energy synchotron radiation (LS-CAT beam-lines at the Argonne National Laboratory) The Post-doctoral fellow will work under the direction of the Center Director and Managing Director, Drs. Janet Smith and Jeanne Stuckey, and work in collaboration with members of the CRNA. The successful candidate will apply their energy and expertise to cutting edge science by: - Designing and executing experiments in collaboration with others. Working in an independent manner. - Maintain clear laboratory notebooks, perform quantitative analyses, and communicate findings through reports and summaries. - Provide detailed documentation so experiments can be replicated. - Follow laboratory best practices for safety and quality. - Being an excellent & proactive communicator, both verbally in writing. - Carrying out innovative research resulting in co- and lead-authored publications on structures of biological importance. - Executing your grasp of modern cloning, expression and purification methodologies. - Developing novel crystallization techniques. - Performing crystallization screens. - Solving and Refining structures. -- Rebecca Epstein Administrative Assistant Senior University of Michigan Life Sciences Institute - CCG/CSB/CDNM 210 Washtenaw Avenue, Room 3338 Ann Arbor, MI 48109-2216 reb...@umich.edu 734.615.9317