The Goldman group in the Department of Biosciences at the University of Helsinki invites applications for:
A postdoctoral researcher in structural studies on protozoan membrane-bound pyrophosphatases with effect from 1.9.2014, until 31.12.2015. Location: Biocentre 2, Viikinkaari 5, Helsinki University. The project is focused on the elucidation of the structure and function of protozoan membrane-bound pyrophosphatases (see Kellosalo et. al. 2012: Science 27, Vol 337). Analyzed proteins are putative drug targets against protozoan parasites, which cause severe infections like malaria, leishmaniasis, African trypanosomiasis and Chaga's disease. The position requires a strong background in protein purification, the capacity to work in a team and independently, the ability to look critically at the results as well as excellent interpersonal and communication skills. The project involves production, purification and functional characterization of protozoan membrane-bound pyrophosphatases, solving of the structures of these proteins with X-ray crystallography and screening of drug compounds in vitro and in vivo. The aim of the project is to discover lead molecules, which can be utilized in the design of anti-protozoan drugs. The successful candidate must hold a PhD degree in biochemistry, chemistry, biophysics or a related field. Excellent background in protein purification documented by peer-reviewed articles is required. Knowledge of screening of drug molecules and X-ray crystallography will be advantageous. Excellent English is also essential in the position. The application should include a complete CV including education, degrees obtained, a list of publications, prior work experience and the names and contact information for two referees. The applications (in English) should be sent to: Docent Taru Meri, P.O. Box 56, FIN-00014 UNIVERSITY OF HELSINKI, Finland or by email to taru.m...@helsinki.fi. The deadline for applications is 4 August 2014. For more information please contact Adrian Goldman, tel. +44 79 18951821; adrian.gold...@helsinki.fi
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