Dear all,

A quick question regarding the density modification interface via the Sharp interface. Which resolution range / radius of the solvent sphere/ ncycles should be used for optimal result? The documentation seems to suggest to restrict yourself up to the resolution where good phasing information is available (6.5A in my case) and I get excellent indicators only if I do that (they become horrible if I use the full resolution range). How about phase extension ? Which parameters would you then use?


Thanks,

Nicolas


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Nicolas Soler
Roger Williams group
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge CB2 0QH
United Kingdom
phone : +44(0) 1223 26 76 20
mail : nso...@mrc-lmb.cam.ac.uk

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