Postdoctoral Position in Structural Biology of Chromatin Regulators in
Grenoble
A 2-year post-doctoral position is available in the newly established
group of Jan Kadlec at the Institut de Biologie Structurale (IBS) in
Grenoble, France to study the structure and function of chromatin
regulatory complexes. The main focus will be on MOF histone
acetyltransferase containing complexes. We use an interdisciplinary
approach combining structural biology (primarily X-ray crystallography),
biochemistry, cell biology and genetics (see Kadlec et al, NSMB
18:142-149 (2011), Hallacli et al, Mol. Cell 48:587-600 (2012), Dias et
al, Genes Dev. 28: 929-942 (2014)).
The IBS is a member of the Partnership for Structural Biology
(www.psb-grenoble.eu) providing access to integrated state-of-the-art
structural biology technologies, including ESRF synchrotron X-ray
beamlines for MX and SAXS, cryo-EM/tomography and NMR as well as
biophysics, confocal microscopy and high-throughput crystallization
platforms.
The successful candidate will be highly motivated and have recently
acquired a PhD in the field of biochemistry/structural biology. Skills
in complex sample preparation methods (protein expression and
purification) are required and experience in protein crystallography
would be an advantage.
Interested applicants should directly contact Jan Kadlec
(kad...@embl.fr).