Postdoctoral Position in Structural Biology of Chromatin Regulators in Grenoble

A 2-year post-doctoral position is available in the newly established group of Jan Kadlec at the Institut de Biologie Structurale (IBS) in Grenoble, France to study the structure and function of chromatin regulatory complexes. The main focus will be on MOF histone acetyltransferase containing complexes. We use an interdisciplinary approach combining structural biology (primarily X-ray crystallography), biochemistry, cell biology and genetics (see Kadlec et al, NSMB 18:142-149 (2011), Hallacli et al, Mol. Cell 48:587-600 (2012), Dias et al, Genes Dev. 28: 929-942 (2014)).

The IBS is a member of the Partnership for Structural Biology (www.psb-grenoble.eu) providing access to integrated state-of-the-art structural biology technologies, including ESRF synchrotron X-ray beamlines for MX and SAXS, cryo-EM/tomography and NMR as well as biophysics, confocal microscopy and high-throughput crystallization platforms.

The successful candidate will be highly motivated and have recently acquired a PhD in the field of biochemistry/structural biology. Skills in complex sample preparation methods (protein expression and purification) are required and experience in protein crystallography would be an advantage.

Interested applicants should directly contact Jan Kadlec (kad...@embl.fr).

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