Dear all

I have a dimer that is related to each other by a crystallographic symmetry. My 
questions are:

a. how reliable are the delta G values given by PISA? Has there been an 
experimental study?

b. For a dissociation delta G of say, around 30 kcal/mol, is it possible to 
estimate the sort of chemical forces (pH or ionic strength) that will be needed 
to experimentally produce the monomer?

Thanks.
Mohamed

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