I presume you set te occupancy to 0.5? if it is a 2fold.. eleanor
On 26 May 2017 at 19:35, jeorgemarley thomas <kirtswab...@gmail.com> wrote: > Dear all, > I encountered a positive density of water molecule (probably) at the > symmetry axis of the protein molecule (resolution 1.75 Ang) . After > refinement with water it shows negative density around it. Can anybody > please explain the possible reason for this and how such problems can be > resolved. I am attaching the snapshots of situation before and after > refinement. > > Thank you > regards > Jeorge >
