Well - the S f" is only ~ 0.5 at Cu Kalpha so the signal will be very weak.. Very accurate data may get a solution but you first have to position the S atoms...
Much easier to try to make a heavy atom derivative! Eleanor On 3 April 2018 at 15:26, Manoj Saxena < 00001d16aa30e8a1-dmarc-requ...@jiscmail.ac.uk> wrote: > Hi All, > > I am writing to seek advice on doing sulphur SAD data collection > at Cu based home source for a protein that is 12 KDa and has 6 S atoms. > I have seen some links online and some references but would be grateful if > you can share your know-how for success with this. > Like what multiplicity of data would be good to aim for and > data processing tips. > Inputs from people who have tried and failed would also be highly > appreciated. > > Thank you > Manoj Saxena > University of Puerto Rico > > >
