The Lee lab in the Department of Pharmacology at the Yale School of Medicine has an immediate opening for a highly motivated Postdoctoral Associate to investigate the molecular mechanism of endocrine Fibroblast Growth Factor (FGF) signaling. Endocrine FGFs, which include, FGF15/19, FGF21, and FGF23, activate signaling via FGF receptors and require binding to the Klotho family of surface receptors; FGF23 signaling requires α-Klotho, while FGF15/19 and FGF21 signaling requires β-Klotho. The research in our laboratory is focused on the structural elucidation, biophysical and biochemical analyses of complexes involved in endocrine FGF signaling.
Applicants should have a PhD in biochemistry, biophysics or a related field and should have extensive experience in recombinant protein production, as well as excellent written and oral communication skills. Experience in structural biology techniques (X-ray crystallography or cryo-EM), mammalian cell culture and quantitative biophysical analyses are also desirable, but not necessary. Interested candidates should send a current CV, a statement of research interests, and the names and contact information of two references to Sangwon Lee (s....@yale.edu). ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
